[Amath-seminars] Tuesday Feb. 16 - Special AMATH Seminar - Shishi Luo (UCB)

Ulrich Hetmaniuk hetmaniu at uw.edu
Mon Feb 15 15:56:58 PST 2016


Dear All,

Here is a kind reminder about Shishi Luo's presentation on Tuesday Feb.
16th at 16h00 in Dempsey Hall DEM 004.

Speaker: Shishi Luo, UCB
Time: February 16th, 16h00
Location: DEM 004 (Dempsey Hall)

Title: Mathematical biology in the genomics era



> Abstract

> -----------

> Biology is becoming increasingly quantitative, with large genomic datasets

> being curated at a rapid rate. Both theoretical and data-driven approaches

> are required to take advantage of these newly available datasets. I will

> describe two projects in the field of evolutionary biology that span the

> spectrum of these approaches. The first project is the development and

> analysis of a Markov chain model of natural selection acting at two scales.

> Simulations of the stochastic process as well as analysis of the scaling

> limit lead to general properties of this complex evolutionary phenomenon.

> The second project is a bioinformatics pipeline that identifies gene copy

> number variants, currently a difficult problem in modern genomics. Using

> hierarchical clustering to define a reference set of genes, we can

> represent inter-individual variation in gene copy number in a tractable

> form. This quantification of copy number variation in turn generates new

> mathematical modeling questions that require the type of approach described

> in the first part of my talk.

>

> Speaker webpage

> ------------------------

> https://szluo.wordpress.com/

>

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