[Amath-seminars] Tuesday Feb. 16 - Special AMATH Seminar -
Shishi Luo (UCB)
hetmaniu at uw.edu
Mon Feb 15 15:56:58 PST 2016
Here is a kind reminder about Shishi Luo's presentation on Tuesday Feb.
16th at 16h00 in Dempsey Hall DEM 004.
Speaker: Shishi Luo, UCB
Time: February 16th, 16h00
Location: DEM 004 (Dempsey Hall)
Title: Mathematical biology in the genomics era
> Biology is becoming increasingly quantitative, with large genomic datasets
> being curated at a rapid rate. Both theoretical and data-driven approaches
> are required to take advantage of these newly available datasets. I will
> describe two projects in the field of evolutionary biology that span the
> spectrum of these approaches. The first project is the development and
> analysis of a Markov chain model of natural selection acting at two scales.
> Simulations of the stochastic process as well as analysis of the scaling
> limit lead to general properties of this complex evolutionary phenomenon.
> The second project is a bioinformatics pipeline that identifies gene copy
> number variants, currently a difficult problem in modern genomics. Using
> hierarchical clustering to define a reference set of genes, we can
> represent inter-individual variation in gene copy number in a tractable
> form. This quantification of copy number variation in turn generates new
> mathematical modeling questions that require the type of approach described
> in the first part of my talk.
> Speaker webpage
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