[Popgenlunch] Abigail Bigham on Wed May 9th - On the Top of World: Human Adaptation to High Altitude

Dan T.A. Eisenberg dtae at uw.edu
Thu May 3 21:35:05 PDT 2018


Talk of possible interest.

-Dan



--
Dan T.A. Eisenberg
Associate Professor
Department of Anthropology
University of Washington
Campus Box 353100
Seattle, WA 98195
Office: Denny 138
Lab: Kincaid 038
www.dtae.net


-------- Forwarded Message --------
Subject: [Csssfac] Meeting with CSSS Seminar Speaker Abigail Bigham on Wed
May 9th
Date: Mon, 30 Apr 2018 12:08:26 -0700
From: Jeffrey B. Arnold <jrnold at uw.edu> <jrnold at uw.edu>
To: csssfac at uw.edu, csssgrads at uw.edu

Hi all,

If you would like to meet with next week's CSSS seminar speaker, on
Wednesday, May 9, please sign up using this* link
<https://doodle.com/poll/2pn8f2sfu94r7fzu>.*

There are 30-minute meeting slots in the morning (9:00 am-11:00 am) and
afternoon (2 pm-4:00 pm).

More information about her and her talk is below.

- Jeff

Wednesday, May 9︱ 12:30–1:30pm ︱Savery (SAV) 409
<http://www.washington.edu/maps/#%21/sav>

*On the Top of World: Human Adaptation to High Altitude
<https://www.csss.washington.edu/seminars/599>*

*Abigail Bigham <https://sites.lsa.umich.edu/bigham-lab/>*
*Assistant Professor of Anthropology at the University of Michigan*

High-altitude environments, defined as areas lying above 2,500 meters [m]
sea-level, challenge the ability of humans to live and reproduce, i.e.,
adapt and/or acclimatize. Hypoxia is the fundamental challenge that
high-altitude sojourners and residents face, necessitating physiological
acclimatization and/or genetic adaptation to overcome it. Long-resident
populations of high altitude, Tibetans and Andeans, show genomic evidence
of adaptation and significant genotype associations with altitude-adaptive
phenotypes. Ongoing research is working towards identifying the functional
consequence of altitude-adaptive variation. Together, these results provide
key insights into the patterns of genetic adaptation to high altitude, shed
light on genetic variation contributing to complex phenotypes, and are of
potential importance for public health given HIF-pathway involvement with
various disease processes, e.g., chronic ischemic disease, regulation of
tumor growth.

*About the Series*

The weekly Center for Statistics and the Social Sciences (CSSS
<https://www.csss.washington.edu/>) seminar provides a forum for local and
visiting scholars to present current research at the interface of
statistics and the social sciences. Talks range in their level of technical
detail and substantive motivation, and often result in spirited discussion.
Students may receive credit for attending the seminar by enrolling in CS&SS
590 All seminars are held at 12:30 on Wednesdays in Savery (SAV) 409
<http://www.washington.edu/maps/#%21/sav> unless otherwise noted, and we
will aim to conclude by 1:30. We provide coffee and light refreshments;
attendees are also welcome to bring their lunch. For information or
questions about the CSSS Seminars, please contact our Seminar Director,
Jeffrey Arnold ( jrnold at uw.edu). You can receive updates via a mailing list
<https://mailman13.u.washington.edu/mailman/listinfo/csss-seminar> or
calendar
<https://admin.stat.washington.edu/v1/calendars/csss-seminars?format=ics>.

You can unsubscribe from this list or change your preferences at
https://mailman13.u.washington.edu/mailman/listinfo/csss-seminar.

--
Jeffrey Arnold
University of Washington
Assistant Professor of Political Science
Core Faculty Member of the Center for Statistics and the Social Sciences
http://jrnold.me

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